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[1] [2] Additional important safety considerations include risk of pancreatitis, gallbladder disease, hypoglycemia (especially when used with insulin or sulfonylureas), and acute kidney injury associated with severe gastrointestinal adverse reactions

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29 In a systematic review and meta-analysis pooling these and other studies, Amaral et al found that the risk of glaucoma development was lower in patients taking GLP-1 RAs (HR = .71) compared with controls